Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Histone-binding protein RBBP4/Histone-lysine N-methyltransferase EZH2/Polycomb protein EED/Polycomb protein SUZ12/Zinc finger protein AEBP2' and Ligand = 'BDBM513658'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone-binding protein RBBP4/Histone-lysine N-methyltransferase EZH2/Polycomb protein EED/Polycomb protein SUZ12/Zinc finger protein AEBP2 (Homo sapiens (Human))	BDBM513658 (US11091495, Example 20 | US11220509, Example 20 | ...) Show SMILES CNC(=O)c1cn2c(NCc3c4CCOc4ccc3F)ncc(-c3cc(C)nn3C)c2n1 Show InChI	PDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...				Citation and Details BindingDB Entry DOI: 10.7270/Q2V69NQ4
					More data for this Ligand-Target Pair
Histone-binding protein RBBP4/Histone-lysine N-methyltransferase EZH2/Polycomb protein EED/Polycomb protein SUZ12/Zinc finger protein AEBP2 (Homo sapiens (Human))	BDBM513658 (US11091495, Example 20 | US11220509, Example 20 | ...) Show SMILES CNC(=O)c1cn2c(NCc3c4CCOc4ccc3F)ncc(-c3cc(C)nn3C)c2n1 Show InChI	PDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...				Citation and Details BindingDB Entry DOI: 10.7270/Q2J969K9
					More data for this Ligand-Target Pair
Histone-binding protein RBBP4/Histone-lysine N-methyltransferase EZH2/Polycomb protein EED/Polycomb protein SUZ12/Zinc finger protein AEBP2 (Homo sapiens (Human))	BDBM513658 (US11091495, Example 20 | US11220509, Example 20 | ...) Show SMILES CNC(=O)c1cn2c(NCc3c4CCOc4ccc3F)ncc(-c3cc(C)nn3C)c2n1 Show InChI	PDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...				Citation and Details BindingDB Entry DOI: 10.7270/Q2J969K9
					More data for this Ligand-Target Pair