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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Histone-lysine N-methyltransferase 2A/Menin' and Ligand = 'BDBM470584'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histone-lysine N-methyltransferase 2A/Menin


(Homo sapiens (Human))		BDBM470584
PNG
(US10815241, Example 9 | US11369605, Example 9)
Show SMILES CC(C)N(C(C)C)C(=O)c1cc(F)ccc1Oc1cncnc1N1CC2(CN(C2)C(=O)[C@H]2N[C@H]3CC[C@@H]2CC3=C)C1
Show InChI InChI=1S/C31H39FN6O3/c1-18(2)38(19(3)4)29(39)23-11-22(32)7-9-25(23)41-26-12-33-17-34-28(26)36-13-31(14-36)15-37(16-31)30(40)27-21-6-8-24(35-27)20(5)10-21/h7,9,11-12,17-19,21,24,27,35H,5-6,8,10,13-16H2,1-4H3/t21-,24+,27+/m1/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 6.20n/an/an/an/an/an/a


TBA

Assay Description
Menin1-615 wherein 6×His tag and HA tag are inserted in the N-terminus, and myc tag is inserted in the C-terminus (hereinafter, referred to as His-Me...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2X63R5J
More data for this
Ligand-Target Pair