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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Histone-lysine N-methyltransferase EHMT2' and Ligand = 'BDBM50512661'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histone-lysine N-methyltransferase EHMT2


(Homo sapiens (Human))		BDBM50512661
PNG
(CHEMBL4438513)
Show SMILES CCN1CCC(CC1)c1cc2nc(nc(NC3CCN(C)CC3)c2cc1OC)N1CCCN(C)CC1
Show InChI InChI=1S/C28H45N7O/c1-5-34-15-7-21(8-16-34)23-19-25-24(20-26(23)36-4)27(29-22-9-13-33(3)14-10-22)31-28(30-25)35-12-6-11-32(2)17-18-35/h19-22H,5-18H2,1-4H3,(H,29,30,31)
PDB

UniProtKB/SwissProt

GoogleScholar
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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 142n/an/an/an/an/an/a



Mercachem BV

Curated by ChEMBL


Assay Description
Inhibition of N-terminal GST tagged human recombinant EHMT2 (785 to 1210 residues) expressed in baculovirus infected Sf9 insect cells assessed as red...

Bioorg Med Chem Lett 29: 2516-2524 (2019)


Article DOI: 10.1016/j.bmcl.2019.06.012
BindingDB Entry DOI: 10.7270/Q2ZW1Q8X
More data for this
Ligand-Target Pair