Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Hormone-sensitive lipase' and Ligand = 'BDBM120369'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hormone-sensitive lipase (Homo sapiens (Human))	BDBM120369 (US8703807, 5) Show SMILES CC(C)Oc1ccc(cc1)N1CC[C@]2(CC[C@@](O)(COCC(F)F)CC2)C1=O |r,wU:13.27,16.17,wD:16.18,(7.2,2.13,;8.68,1.73,;9.77,2.82,;8.29,.24,;6.8,-.16,;6.4,-1.64,;4.91,-2.04,;3.82,-.95,;4.22,.53,;5.71,.93,;2.33,-1.35,;1.86,-2.82,;.32,-2.82,;-.16,-1.35,;-.56,.13,;-2.04,.53,;-3.13,-.56,;-3.53,.93,;-4.22,-1.64,;-5.71,-1.25,;-6.8,-2.34,;-8.29,-1.94,;-9.77,-1.54,;-7.89,-.45,;-2.73,-2.04,;-1.25,-2.44,;1.09,-.45,;1.09,1.09,)| Show InChI InChI=1S/C21H29F2NO4/c1-15(2)28-17-5-3-16(4-6-17)24-12-11-20(19(24)25)7-9-21(26,10-8-20)14-27-13-18(22)23/h3-6,15,18,26H,7-14H2,1-2H3/t20-,21+	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	16.3	n/a	n/a	n/a	n/a	7.2	4
Hoffmann-La Roche Inc. US Patent					Assay Description HSL enzyme activity was measured by a colorimetric assay using 2,3-dimercapto-1-propanol tributyrate (Aldrich, St. Louis, Mo.) as a substrate. Typica...				US Patent US8703807 (2014) BindingDB Entry DOI: 10.7270/Q2RN36HB
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