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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Hormone-sensitive lipase' and Ligand = 'BDBM50138731'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hormone-sensitive lipase


(Rattus norvegicus (Rat))
BDBM50138731
PNG
(3-(4-Chloro-phenyl)-5-ethylsulfanyl-[1,2,4]triazol...)
Show SMILES CCSc1nc(nn1C(=O)N(C)C)-c1ccc(Cl)cc1
Show InChI InChI=1S/C13H15ClN4OS/c1-4-20-12-15-11(9-5-7-10(14)8-6-9)16-18(12)13(19)17(2)3/h5-8H,4H2,1-3H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.71n/an/an/an/an/an/a



University of Jordan

Curated by ChEMBL


Assay Description
Inhibition of HSL in Wistar rat isolated fat cells by spectrophotometric assay


J Med Chem 51: 6478-94 (2008)


Article DOI: 10.1021/jm800718k
BindingDB Entry DOI: 10.7270/Q23778KJ
More data for this
Ligand-Target Pair
Hormone-sensitive lipase


(Homo sapiens (Human))
BDBM50138731
PNG
(3-(4-Chloro-phenyl)-5-ethylsulfanyl-[1,2,4]triazol...)
Show SMILES CCSc1nc(nn1C(=O)N(C)C)-c1ccc(Cl)cc1
Show InChI InChI=1S/C13H15ClN4OS/c1-4-20-12-15-11(9-5-7-10(14)8-6-9)16-18(12)13(19)17(2)3/h5-8H,4H2,1-3H3
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 210n/an/an/an/an/an/a



Novo Nordisk A/S

Curated by ChEMBL


Assay Description
Inhibition of hormone sensitive lipase (HSL).


J Med Chem 47: 400-10 (2004)


Article DOI: 10.1021/jm031004s
BindingDB Entry DOI: 10.7270/Q2ZG6RN1
More data for this
Ligand-Target Pair