Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Hormone-sensitive lipase' and Ligand = 'BDBM99482'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hormone-sensitive lipase (Homo sapiens (Human))	BDBM99482 (US8501768, 10) Show SMILES CC(C)CS(=O)(=O)N1C[C@@H]2CCN(C(=O)[C@@H]2C1)c1ccc(OC(F)(F)F)cc1 |r| Show InChI InChI=1S/C18H23F3N2O4S/c1-12(2)11-28(25,26)22-9-13-7-8-23(17(24)16(13)10-22)14-3-5-15(6-4-14)27-18(19,20)21/h3-6,12-13,16H,7-11H2,1-2H3/t13-,16+/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	956	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description HSL enzyme activity was measured by a colorimetric assay.				US Patent US8501768 (2013) BindingDB Entry DOI: 10.7270/Q26Q1VW3
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