Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Hormone-sensitive lipase' and Ligand = 'BDBM99484'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hormone-sensitive lipase (Homo sapiens (Human))	BDBM99484 (US8501768, 12) Show SMILES Fc1ccc(cc1)S(=O)(=O)N1C[C@@H]2CCN(C(=O)[C@@H]2C1)c1ccc(OC(F)(F)F)cc1 |r| Show InChI InChI=1S/C20H18F4N2O4S/c21-14-1-7-17(8-2-14)31(28,29)25-11-13-9-10-26(19(27)18(13)12-25)15-3-5-16(6-4-15)30-20(22,23)24/h1-8,13,18H,9-12H2/t13-,18+/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	380	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description HSL enzyme activity was measured by a colorimetric assay.				US Patent US8501768 (2013) BindingDB Entry DOI: 10.7270/Q26Q1VW3
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