Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Hormone-sensitive lipase' and Ligand = 'BDBM99489'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hormone-sensitive lipase (Homo sapiens (Human))	BDBM99489 (US8501768, 17) Show SMILES FC(F)(F)COc1ccc(cc1)N1CC[C@@H]2CN(C[C@@H]2C1=O)S(=O)(=O)c1ccccc1OC(F)(F)F |r| Show InChI InChI=1S/C22H20F6N2O5S/c23-21(24,25)13-34-16-7-5-15(6-8-16)30-10-9-14-11-29(12-17(14)20(30)31)36(32,33)19-4-2-1-3-18(19)35-22(26,27)28/h1-8,14,17H,9-13H2/t14-,17+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	51.2	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description HSL enzyme activity was measured by a colorimetric assay.				US Patent US8501768 (2013) BindingDB Entry DOI: 10.7270/Q26Q1VW3
					More data for this Ligand-Target Pair