Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Hormone-sensitive lipase' and Ligand = 'BDBM99497'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hormone-sensitive lipase (Homo sapiens (Human))	BDBM99497 (US8501768, 25) Show SMILES CC(C)(C)OC(=O)N1C[C@H]2CCN(C(=O)[C@H]2C1)c1ccc(OCC(F)(F)F)cc1 |r| Show InChI InChI=1S/C20H25F3N2O4/c1-19(2,3)29-18(27)24-10-13-8-9-25(17(26)16(13)11-24)14-4-6-15(7-5-14)28-12-20(21,22)23/h4-7,13,16H,8-12H2,1-3H3/t13-,16+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	334	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description HSL enzyme activity was measured by a colorimetric assay.				US Patent US8501768 (2013) BindingDB Entry DOI: 10.7270/Q26Q1VW3
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