Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Hormone-sensitive lipase' and Ligand = 'BDBM99505'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hormone-sensitive lipase (Homo sapiens (Human))	BDBM99505 (US8501768, 33) Show SMILES FC(F)(F)Oc1ccc(cc1)N1C[C@@H]2CC(C[C@@H]2C1=O)NS(=O)(=O)c1ccccc1Cl |r| Show InChI InChI=1S/C20H18ClF3N2O4S/c21-17-3-1-2-4-18(17)31(28,29)25-13-9-12-11-26(19(27)16(12)10-13)14-5-7-15(8-6-14)30-20(22,23)24/h1-8,12-13,16,25H,9-11H2/t12-,13?,16-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	96.5	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description HSL enzyme activity was measured by a colorimetric assay.				US Patent US8501768 (2013) BindingDB Entry DOI: 10.7270/Q26Q1VW3
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