BindingDB PrimarySearch

Found 2 hits Enz. Inhib. hit(s) with Target = 'Hydroxycarboxylic acid receptor 2' and Ligand = 'BDBM50264264'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50264264 ((R)-3-(4-isopropylphenyl)-7-methyl-N-(1-phenoxypro...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MCE PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]nicotinic acid from human GPR109A receptor expressed in CHO cells				Bioorg Med Chem Lett 18: 4948-51 (2008) Article DOI: 10.1016/j.bmcl.2008.08.039 BindingDB Entry DOI: 10.7270/Q2DZ0843
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50264264 ((R)-3-(4-isopropylphenyl)-7-methyl-N-(1-phenoxypro...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MCE PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	120	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Agonist activity at human GPR109A receptor expressed in CHO cells by [35S]GTPgammaS binding assay				Bioorg Med Chem Lett 18: 4948-51 (2008) Article DOI: 10.1016/j.bmcl.2008.08.039 BindingDB Entry DOI: 10.7270/Q2DZ0843
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)