Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Hypoxanthine-guanine phosphoribosyltransferase' and Ligand = 'BDBM50519493'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hypoxanthine-guanine phosphoribosyltransferase (Homo sapiens (Human))	BDBM50519493 (CHEMBL4453040) Show SMILES OC[C@@H](Cn1cnc2c1nc[nH]c2=O)n1cc(nn1)P(O)(O)=O |r| Show InChI InChI=1S/C10H12N7O5P/c18-3-6(17-2-7(14-15-17)23(20,21)22)1-16-5-13-8-9(16)11-4-12-10(8)19/h2,4-6,18H,1,3H2,(H,11,12,19)(H2,20,21,22)/t6-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Montpellier Curated by ChEMBL					Assay Description Inhibition of human HGPRT using Prib-PP as substrate by Hanes-plot based method				J Med Chem 62: 8365-8391 (2019) Article DOI: 10.1021/acs.jmedchem.9b00182 BindingDB Entry DOI: 10.7270/Q2T1571N
					More data for this Ligand-Target Pair