Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Hypoxanthine-guanine phosphoribosyltransferase' and Ligand = 'BDBM50519505'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hypoxanthine-guanine phosphoribosyltransferase (Homo sapiens (Human))	BDBM50519505 (CHEMBL4578350) Show SMILES COC(=O)[C@H](Cn1cnc2c1nc[nH]c2=O)OCCP(O)(O)=O |r| Show InChI InChI=1S/C11H15N4O7P/c1-21-11(17)7(22-2-3-23(18,19)20)4-15-6-14-8-9(15)12-5-13-10(8)16/h5-7H,2-4H2,1H3,(H,12,13,16)(H2,18,19,20)/t7-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Montpellier Curated by ChEMBL					Assay Description Inhibition of human N-terminal His6-tagged HGPRT using Prib-PP as substrate by Hanes-plot based method				J Med Chem 62: 8365-8391 (2019) Article DOI: 10.1021/acs.jmedchem.9b00182 BindingDB Entry DOI: 10.7270/Q2T1571N
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