Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Hypoxanthine-guanine-xanthine phosphoribosyltransferase (Plasmodium falciparum) | BDBM60880![]() (US9200020, Table 1, Compound 1B) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | US Patent | 300 | -38.7 | n/a | n/a | n/a | n/a | n/a | n/a | 37 |
THE UNIVERSITY OF QUEENSLAND; INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ASCR, V.V.I. US Patent | Assay Description The [3H]-hypoxanthine growth inhibition assay (Desjardins et al., 1979 Antimicrobial Agents Chemother 16: 710-718) was used to evaluate the in vitr... | US Patent US9200020 (2015) BindingDB Entry DOI: 10.7270/Q2TM78XB | |||||||||||
More data for this Ligand-Target Pair |