Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'IgG receptor FcRn large subunit p51' and Ligand = 'BDBM50270947'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
IgG receptor FcRn large subunit p51 (Homo sapiens (Human))	BDBM50270947 ((2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S...) Show SMILES [#6]-[#6](-[#6])-[#6]-[#6@H](-[#7](-[#6])-[#6](=O)-[#6]-[#7](-[#6])-[#6](=O)-[#6]-[#7]-[#6](=O)-[#6@H](-[#6]-c1ccccc1)-[#7]-[#6](=O)-[#6@H](-[#6]-c1ccc(cc1)\[#7]=[#6](\[#7])-[#7])-[#7]-[#6](=O)-[#6]-[#7]-[#6](=O)-[#6@@H](-[#7]-[#6](=O)-[#6@@H](-[#7]-[#6](=O)-[#6@H](-[#6]-c1ccccc1)-[#7]-[#6](=O)-[#6@@H](-[#7])-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])C([#6])([#6])[#16])-[#6@@H](-[#6])-[#8])-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccc(-[#8])cc1)-[#6](=O)-[#7]-1-[#6]-[#6]-[#6]-[#6@H]-1-[#6](=O)-[#7]-[#6@@H](-[#6]-[#16])-[#6](-[#8])=O |r| Show InChI InChI=1S/C74H105N19O16S2/c1-41(2)32-56(67(104)87-53(36-46-24-28-48(95)29-25-46)70(107)93-31-15-21-55(93)66(103)88-54(40-110)71(108)109)92(7)59(98)39-91(6)58(97)38-82-63(100)50(33-43-16-10-8-11-17-43)86-64(101)51(35-45-22-26-47(27-23-45)83-73(78)79)84-57(96)37-81-68(105)60(42(3)94)89-69(106)61(74(4,5)111)90-65(102)52(34-44-18-12-9-13-19-44)85-62(99)49(75)20-14-30-80-72(76)77/h8-13,16-19,22-29,41-42,49-56,60-61,94-95,110-111H,14-15,20-21,30-40,75H2,1-7H3,(H,81,105)(H,82,100)(H,84,96)(H,85,99)(H,86,101)(H,87,104)(H,88,103)(H,89,106)(H,90,102)(H,108,109)(H4,76,77,80)(H4,78,79,83)/t42-,49+,50+,51+,52+,53+,54+,55+,56+,60+,61-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Syntonix Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of human IgG binding to soluble human FcRn by ELISA				Bioorg Med Chem 16: 6394-405 (2008) Article DOI: 10.1016/j.bmc.2008.05.004 BindingDB Entry DOI: 10.7270/Q2QV3M9C
					More data for this Ligand-Target Pair
IgG receptor FcRn large subunit p51 (Homo sapiens (Human))	BDBM50270947 ((2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S...) Show SMILES [#6]-[#6](-[#6])-[#6]-[#6@H](-[#7](-[#6])-[#6](=O)-[#6]-[#7](-[#6])-[#6](=O)-[#6]-[#7]-[#6](=O)-[#6@H](-[#6]-c1ccccc1)-[#7]-[#6](=O)-[#6@H](-[#6]-c1ccc(cc1)\[#7]=[#6](\[#7])-[#7])-[#7]-[#6](=O)-[#6]-[#7]-[#6](=O)-[#6@@H](-[#7]-[#6](=O)-[#6@@H](-[#7]-[#6](=O)-[#6@H](-[#6]-c1ccccc1)-[#7]-[#6](=O)-[#6@@H](-[#7])-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])C([#6])([#6])[#16])-[#6@@H](-[#6])-[#8])-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccc(-[#8])cc1)-[#6](=O)-[#7]-1-[#6]-[#6]-[#6]-[#6@H]-1-[#6](=O)-[#7]-[#6@@H](-[#6]-[#16])-[#6](-[#8])=O |r| Show InChI InChI=1S/C74H105N19O16S2/c1-41(2)32-56(67(104)87-53(36-46-24-28-48(95)29-25-46)70(107)93-31-15-21-55(93)66(103)88-54(40-110)71(108)109)92(7)59(98)39-91(6)58(97)38-82-63(100)50(33-43-16-10-8-11-17-43)86-64(101)51(35-45-22-26-47(27-23-45)83-73(78)79)84-57(96)37-81-68(105)60(42(3)94)89-69(106)61(74(4,5)111)90-65(102)52(34-44-18-12-9-13-19-44)85-62(99)49(75)20-14-30-80-72(76)77/h8-13,16-19,22-29,41-42,49-56,60-61,94-95,110-111H,14-15,20-21,30-40,75H2,1-7H3,(H,81,105)(H,82,100)(H,84,96)(H,85,99)(H,86,101)(H,87,104)(H,88,103)(H,89,106)(H,90,102)(H,108,109)(H4,76,77,80)(H4,78,79,83)/t42-,49+,50+,51+,52+,53+,54+,55+,56+,60+,61-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	74	n/a	n/a	n/a	6.0	n/a
Syntonix Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Binding affinity to human FcRn at pH 6 by surface plasmon resonance assay				Bioorg Med Chem 16: 6394-405 (2008) Article DOI: 10.1016/j.bmc.2008.05.004 BindingDB Entry DOI: 10.7270/Q2QV3M9C
					More data for this Ligand-Target Pair
IgG receptor FcRn large subunit p51 (Homo sapiens (Human))	BDBM50270947 ((2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S...) Show SMILES [#6]-[#6](-[#6])-[#6]-[#6@H](-[#7](-[#6])-[#6](=O)-[#6]-[#7](-[#6])-[#6](=O)-[#6]-[#7]-[#6](=O)-[#6@H](-[#6]-c1ccccc1)-[#7]-[#6](=O)-[#6@H](-[#6]-c1ccc(cc1)\[#7]=[#6](\[#7])-[#7])-[#7]-[#6](=O)-[#6]-[#7]-[#6](=O)-[#6@@H](-[#7]-[#6](=O)-[#6@@H](-[#7]-[#6](=O)-[#6@H](-[#6]-c1ccccc1)-[#7]-[#6](=O)-[#6@@H](-[#7])-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])C([#6])([#6])[#16])-[#6@@H](-[#6])-[#8])-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccc(-[#8])cc1)-[#6](=O)-[#7]-1-[#6]-[#6]-[#6]-[#6@H]-1-[#6](=O)-[#7]-[#6@@H](-[#6]-[#16])-[#6](-[#8])=O |r| Show InChI InChI=1S/C74H105N19O16S2/c1-41(2)32-56(67(104)87-53(36-46-24-28-48(95)29-25-46)70(107)93-31-15-21-55(93)66(103)88-54(40-110)71(108)109)92(7)59(98)39-91(6)58(97)38-82-63(100)50(33-43-16-10-8-11-17-43)86-64(101)51(35-45-22-26-47(27-23-45)83-73(78)79)84-57(96)37-81-68(105)60(42(3)94)89-69(106)61(74(4,5)111)90-65(102)52(34-44-18-12-9-13-19-44)85-62(99)49(75)20-14-30-80-72(76)77/h8-13,16-19,22-29,41-42,49-56,60-61,94-95,110-111H,14-15,20-21,30-40,75H2,1-7H3,(H,81,105)(H,82,100)(H,84,96)(H,85,99)(H,86,101)(H,87,104)(H,88,103)(H,89,106)(H,90,102)(H,108,109)(H4,76,77,80)(H4,78,79,83)/t42-,49+,50+,51+,52+,53+,54+,55+,56+,60+,61-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	73	n/a	n/a	n/a	7.4	n/a
Syntonix Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Binding affinity to human FcRn at pH 7.4 by surface plasmon resonance assay				Bioorg Med Chem 16: 6394-405 (2008) Article DOI: 10.1016/j.bmc.2008.05.004 BindingDB Entry DOI: 10.7270/Q2QV3M9C
					More data for this Ligand-Target Pair