Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'IgG receptor FcRn large subunit p51' and Ligand = 'BDBM50270948'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
IgG receptor FcRn large subunit p51 (Homo sapiens (Human))	BDBM50270948 ((2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S...) Show SMILES [#6]-[#6](-[#6])-[#6]-[#6@H](-[#7](-[#6])-[#6](=O)-[#6]-[#7](-[#6])-[#6](=O)-[#6]-[#7]-[#6](=O)-[#6@H](-[#6]-c1ccccc1)-[#7]-[#6](=O)-[#6@H](-[#6]-c1ccc(-[#7])cc1)-[#7]-[#6](=O)-[#6]-[#7]-[#6](=O)-[#6@@H](-[#7]-[#6](=O)-[#6@@H](-[#7]-[#6](=O)-[#6@H](-[#6]-c1ccccc1)-[#7]-[#6](=O)-[#6@@H](-[#7])-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])C([#6])([#6])[#16])-[#6@@H](-[#6])-[#8])-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccc(-[#8])cc1)-[#6](=O)-[#7]-1-[#6]-[#6]-[#6]-[#6@H]-1-[#6](=O)-[#7]-[#6@@H](-[#6]-[#16])-[#6](-[#8])=O |r| Show InChI InChI=1S/C73H103N17O16S2/c1-41(2)32-56(67(101)84-53(36-46-24-28-48(92)29-25-46)70(104)90-31-15-21-55(90)66(100)85-54(40-107)71(105)106)89(7)59(95)39-88(6)58(94)38-80-63(97)50(33-43-16-10-8-11-17-43)83-64(98)51(35-45-22-26-47(74)27-23-45)81-57(93)37-79-68(102)60(42(3)91)86-69(103)61(73(4,5)108)87-65(99)52(34-44-18-12-9-13-19-44)82-62(96)49(75)20-14-30-78-72(76)77/h8-13,16-19,22-29,41-42,49-56,60-61,91-92,107-108H,14-15,20-21,30-40,74-75H2,1-7H3,(H,79,102)(H,80,97)(H,81,93)(H,82,96)(H,83,98)(H,84,101)(H,85,100)(H,86,103)(H,87,99)(H,105,106)(H4,76,77,78)/t42-,49+,50+,51+,52+,53+,54+,55+,56+,60+,61-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Syntonix Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of human IgG binding to soluble human FcRn by ELISA				Bioorg Med Chem 16: 6394-405 (2008) Article DOI: 10.1016/j.bmc.2008.05.004 BindingDB Entry DOI: 10.7270/Q2QV3M9C
					More data for this Ligand-Target Pair
IgG receptor FcRn large subunit p51 (Homo sapiens (Human))	BDBM50270948 ((2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S...) Show SMILES [#6]-[#6](-[#6])-[#6]-[#6@H](-[#7](-[#6])-[#6](=O)-[#6]-[#7](-[#6])-[#6](=O)-[#6]-[#7]-[#6](=O)-[#6@H](-[#6]-c1ccccc1)-[#7]-[#6](=O)-[#6@H](-[#6]-c1ccc(-[#7])cc1)-[#7]-[#6](=O)-[#6]-[#7]-[#6](=O)-[#6@@H](-[#7]-[#6](=O)-[#6@@H](-[#7]-[#6](=O)-[#6@H](-[#6]-c1ccccc1)-[#7]-[#6](=O)-[#6@@H](-[#7])-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])C([#6])([#6])[#16])-[#6@@H](-[#6])-[#8])-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccc(-[#8])cc1)-[#6](=O)-[#7]-1-[#6]-[#6]-[#6]-[#6@H]-1-[#6](=O)-[#7]-[#6@@H](-[#6]-[#16])-[#6](-[#8])=O |r| Show InChI InChI=1S/C73H103N17O16S2/c1-41(2)32-56(67(101)84-53(36-46-24-28-48(92)29-25-46)70(104)90-31-15-21-55(90)66(100)85-54(40-107)71(105)106)89(7)59(95)39-88(6)58(94)38-80-63(97)50(33-43-16-10-8-11-17-43)83-64(98)51(35-45-22-26-47(74)27-23-45)81-57(93)37-79-68(102)60(42(3)91)86-69(103)61(73(4,5)108)87-65(99)52(34-44-18-12-9-13-19-44)82-62(96)49(75)20-14-30-78-72(76)77/h8-13,16-19,22-29,41-42,49-56,60-61,91-92,107-108H,14-15,20-21,30-40,74-75H2,1-7H3,(H,79,102)(H,80,97)(H,81,93)(H,82,96)(H,83,98)(H,84,101)(H,85,100)(H,86,103)(H,87,99)(H,105,106)(H4,76,77,78)/t42-,49+,50+,51+,52+,53+,54+,55+,56+,60+,61-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	220	n/a	n/a	n/a	6.0	n/a
Syntonix Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Binding affinity to human FcRn at pH 6 by surface plasmon resonance assay				Bioorg Med Chem 16: 6394-405 (2008) Article DOI: 10.1016/j.bmc.2008.05.004 BindingDB Entry DOI: 10.7270/Q2QV3M9C
					More data for this Ligand-Target Pair
IgG receptor FcRn large subunit p51 (Homo sapiens (Human))	BDBM50270948 ((2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S...) Show SMILES [#6]-[#6](-[#6])-[#6]-[#6@H](-[#7](-[#6])-[#6](=O)-[#6]-[#7](-[#6])-[#6](=O)-[#6]-[#7]-[#6](=O)-[#6@H](-[#6]-c1ccccc1)-[#7]-[#6](=O)-[#6@H](-[#6]-c1ccc(-[#7])cc1)-[#7]-[#6](=O)-[#6]-[#7]-[#6](=O)-[#6@@H](-[#7]-[#6](=O)-[#6@@H](-[#7]-[#6](=O)-[#6@H](-[#6]-c1ccccc1)-[#7]-[#6](=O)-[#6@@H](-[#7])-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])C([#6])([#6])[#16])-[#6@@H](-[#6])-[#8])-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccc(-[#8])cc1)-[#6](=O)-[#7]-1-[#6]-[#6]-[#6]-[#6@H]-1-[#6](=O)-[#7]-[#6@@H](-[#6]-[#16])-[#6](-[#8])=O |r| Show InChI InChI=1S/C73H103N17O16S2/c1-41(2)32-56(67(101)84-53(36-46-24-28-48(92)29-25-46)70(104)90-31-15-21-55(90)66(100)85-54(40-107)71(105)106)89(7)59(95)39-88(6)58(94)38-80-63(97)50(33-43-16-10-8-11-17-43)83-64(98)51(35-45-22-26-47(74)27-23-45)81-57(93)37-79-68(102)60(42(3)91)86-69(103)61(73(4,5)108)87-65(99)52(34-44-18-12-9-13-19-44)82-62(96)49(75)20-14-30-78-72(76)77/h8-13,16-19,22-29,41-42,49-56,60-61,91-92,107-108H,14-15,20-21,30-40,74-75H2,1-7H3,(H,79,102)(H,80,97)(H,81,93)(H,82,96)(H,83,98)(H,84,101)(H,85,100)(H,86,103)(H,87,99)(H,105,106)(H4,76,77,78)/t42-,49+,50+,51+,52+,53+,54+,55+,56+,60+,61-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	1.10E+3	n/a	n/a	n/a	7.4	n/a
Syntonix Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Binding affinity to human FcRn at pH 7.4 by surface plasmon resonance assay				Bioorg Med Chem 16: 6394-405 (2008) Article DOI: 10.1016/j.bmc.2008.05.004 BindingDB Entry DOI: 10.7270/Q2QV3M9C
					More data for this Ligand-Target Pair