Compile Data Set for Download or QSAR

Found 6 hits Enz. Inhib. hit(s) with Target = 'Indoleamine 2,3-dioxygenase 1' and Ligand = 'BDBM222999'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Indoleamine 2,3-dioxygenase 1 (Homo sapiens (Human))	BDBM222999 (US10034864, Example 1 | US10967060, Example 1 | US...) Show SMILES NS(=O)(=O)NCCNc1nonc1C(Nc1ccc(F)c(Br)c1)=NO |w:23.25| Show InChI InChI=1S/C11H13BrFN7O4S/c12-7-5-6(1-2-8(7)13)17-11(18-21)9-10(20-24-19-9)15-3-4-16-25(14,22)23/h1-2,5,16,21H,3-4H2,(H,15,20)(H,17,18)(H2,14,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB US Patent	n/a	n/a	<200	n/a	n/a	n/a	n/a	6.5	25
Incyte Corporation; Incyte Holdings Corporation US Patent					Assay Description Human indoleamine 2,3-dioxygenasae (IDO) with an N-terminal His tag was expressed in E. coli and purified to homogeneity. IDO catalyzes the oxidative...				US Patent US9320732 (2016) BindingDB Entry DOI: 10.7270/Q26M35Q9
					More data for this Ligand-Target Pair				3D Structure (crystal)
Indoleamine 2,3-dioxygenase 1 (Homo sapiens (Human))	BDBM222999 (US10034864, Example 1 | US10967060, Example 1 | US...) Show SMILES NS(=O)(=O)NCCNc1nonc1C(Nc1ccc(F)c(Br)c1)=NO |w:23.25| Show InChI InChI=1S/C11H13BrFN7O4S/c12-7-5-6(1-2-8(7)13)17-11(18-21)9-10(20-24-19-9)15-3-4-16-25(14,22)23/h1-2,5,16,21H,3-4H2,(H,15,20)(H,17,18)(H2,14,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB US Patent	n/a	n/a	<200	n/a	n/a	n/a	n/a	6.5	25
The University of Chicago US Patent					Assay Description Human indoleamine 2,3-dioxygenasae (IDO) with an N-terminal His tag was expressed in E. coli and purified to homogeneity. IDO catalyzes the oxidative...				US Patent US10034939 (2018) BindingDB Entry DOI: 10.7270/Q2NK3H2M
					More data for this Ligand-Target Pair				3D Structure (crystal)
Indoleamine 2,3-dioxygenase 1 (Homo sapiens (Human))	BDBM222999 (US10034864, Example 1 | US10967060, Example 1 | US...) Show SMILES NS(=O)(=O)NCCNc1nonc1C(Nc1ccc(F)c(Br)c1)=NO |w:23.25| Show InChI InChI=1S/C11H13BrFN7O4S/c12-7-5-6(1-2-8(7)13)17-11(18-21)9-10(20-24-19-9)15-3-4-16-25(14,22)23/h1-2,5,16,21H,3-4H2,(H,15,20)(H,17,18)(H2,14,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB US Patent	n/a	n/a	<200	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Human indoleamine 2,3-dioxygenasae (IDO) with an N-terminal His tag was expressed in E. coli and purified to homogeneity. IDO catalyzes the oxidative...				Citation and Details BindingDB Entry DOI: 10.7270/Q2KD222H
					More data for this Ligand-Target Pair				3D Structure (crystal)
Indoleamine 2,3-dioxygenase 1 (Homo sapiens (Human))	BDBM222999 (US10034864, Example 1 | US10967060, Example 1 | US...) Show SMILES NS(=O)(=O)NCCNc1nonc1C(Nc1ccc(F)c(Br)c1)=NO |w:23.25| Show InChI InChI=1S/C11H13BrFN7O4S/c12-7-5-6(1-2-8(7)13)17-11(18-21)9-10(20-24-19-9)15-3-4-16-25(14,22)23/h1-2,5,16,21H,3-4H2,(H,15,20)(H,17,18)(H2,14,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB US Patent	n/a	n/a	<200	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Holdings Corporation; Incyte Corporation US Patent					Assay Description Human indoleamine 2,3-dioxygenasae (IDO) with an N-terminal His tag was expressed in E. coli and purified to homogeneity. IDO catalyzes the oxidative...				US Patent US9789094 (2017) BindingDB Entry DOI: 10.7270/Q27W6F9F
					More data for this Ligand-Target Pair				3D Structure (crystal)
Indoleamine 2,3-dioxygenase 1 (Homo sapiens (Human))	BDBM222999 (US10034864, Example 1 | US10967060, Example 1 | US...) Show SMILES NS(=O)(=O)NCCNc1nonc1C(Nc1ccc(F)c(Br)c1)=NO |w:23.25| Show InChI InChI=1S/C11H13BrFN7O4S/c12-7-5-6(1-2-8(7)13)17-11(18-21)9-10(20-24-19-9)15-3-4-16-25(14,22)23/h1-2,5,16,21H,3-4H2,(H,15,20)(H,17,18)(H2,14,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB US Patent	n/a	n/a	<200	n/a	n/a	n/a	n/a	n/a	n/a
The University of Chicago US Patent					Assay Description Human indoleamine 2,3-dioxygenasae (IDO) with an N-terminal His tag was expressed in E. coli and purified to homogeneity. IDO catalyzes the oxidative...				US Patent US10967060 (2021) BindingDB Entry DOI: 10.7270/Q2XK8JPG
					More data for this Ligand-Target Pair				3D Structure (crystal)
Indoleamine 2,3-dioxygenase 1 (Homo sapiens (Human))	BDBM222999 (US10034864, Example 1 | US10967060, Example 1 | US...) Show SMILES NS(=O)(=O)NCCNc1nonc1C(Nc1ccc(F)c(Br)c1)=NO |w:23.25| Show InChI InChI=1S/C11H13BrFN7O4S/c12-7-5-6(1-2-8(7)13)17-11(18-21)9-10(20-24-19-9)15-3-4-16-25(14,22)23/h1-2,5,16,21H,3-4H2,(H,15,20)(H,17,18)(H2,14,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB US Patent	n/a	n/a	<200	n/a	n/a	n/a	n/a	6.5	25
Incyte Holdings Corporation; Incyte Corporation US Patent					Assay Description Human indoleamine 2,3-dioxygenasae (IDO) with an N-terminal His tag was expressed in E. coli and purified to homogeneity. IDO catalyzes the oxidative...				US Patent US10034864 (2018) BindingDB Entry DOI: 10.7270/Q2SB47SX
					More data for this Ligand-Target Pair				3D Structure (crystal)