Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Indoleamine 2,3-dioxygenase 1' and Ligand = 'BDBM370508'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Indoleamine 2,3-dioxygenase 1 (Homo sapiens (Human))	BDBM370508 (1-cyclohexyl-2-(5H-imidazo[5,1-a]isoindol-5- yl)et...) Show SMILES O=C(Nc1ccccc1)OC(CC1c2ccccc2-c2cncn12)C1CCCCC1 Show InChI InChI=1S/C25H27N3O2/c29-25(27-19-11-5-2-6-12-19)30-24(18-9-3-1-4-10-18)15-22-20-13-7-8-14-21(20)23-16-26-17-28(22)23/h2,5-8,11-14,16-18,22,24H,1,3-4,9-10,15H2,(H,27,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
Bayer HealthCare Pharmaceuticals Corporation					Assay Description The IC50 values for each compound were determined by testing the activity of IDO in a mixture containing 50 mM potassium phosphate buffer at pH 6.5; ...				J Med Chem 50: 984-1000 (2007) BindingDB Entry DOI: 10.7270/Q26H4KQM
					More data for this Ligand-Target Pair