Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Indoleamine 2,3-dioxygenase 1' and Ligand = 'BDBM370522'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Indoleamine 2,3-dioxygenase 1 (Homo sapiens (Human))	BDBM370522 ((2S)-1-cyclohexyl-2-(5H-imidazo[5,1-a]isoindol- 5-...) Show SMILES O=C(OC(CC1c2ccccc2-c2cncn12)C1CCCCC1)[C@@H]1CCCN1 |r| Show InChI InChI=1S/C23H29N3O2/c27-23(19-11-6-12-25-19)28-22(16-7-2-1-3-8-16)13-20-17-9-4-5-10-18(17)21-14-24-15-26(20)21/h4-5,9-10,14-16,19-20,22,25H,1-3,6-8,11-13H2/t19-,20?,22?/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
Bayer HealthCare Pharmaceuticals Corporation					Assay Description The IC50 values for each compound were determined by testing the activity of IDO in a mixture containing 50 mM potassium phosphate buffer at pH 6.5; ...				J Med Chem 50: 984-1000 (2007) BindingDB Entry DOI: 10.7270/Q26H4KQM
					More data for this Ligand-Target Pair