Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Indoleamine 2,3-dioxygenase 1' and Ligand = 'BDBM494721'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Indoleamine 2,3-dioxygenase 1 (Homo sapiens (Human))	BDBM494721 (4-((2-(3- cyclopropylureido)ethyl)thio)-N-(4- fluo...) Show SMILES O\N=C(/NC1Cc2ccc(F)cc12)c1nonc1SCCNC(=O)NC1CC1 Show InChI InChI=1S/C17H19FN6O3S/c18-10-2-1-9-7-13(12(9)8-10)21-15(22-26)14-16(24-27-23-14)28-6-5-19-17(25)20-11-3-4-11/h1-2,8,11,13,26H,3-7H2,(H,21,22)(H2,19,20,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	42.9	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description HIS-tagged IDO1 protein was recombinantly expressed in Escherichia coli using ZYP5052 autoinduction media supplemented with 500 μM delta aminole...				US Patent US10988487 (2021) BindingDB Entry DOI: 10.7270/Q25T3PKG
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Homo sapiens (Human))	BDBM494721 (4-((2-(3- cyclopropylureido)ethyl)thio)-N-(4- fluo...) Show SMILES O\N=C(/NC1Cc2ccc(F)cc12)c1nonc1SCCNC(=O)NC1CC1 Show InChI InChI=1S/C17H19FN6O3S/c18-10-2-1-9-7-13(12(9)8-10)21-15(22-26)14-16(24-27-23-14)28-6-5-19-17(25)20-11-3-4-11/h1-2,8,11,13,26H,3-7H2,(H,21,22)(H2,19,20,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description HIS-tagged IDO1 protein was recombinantly expressed in Escherichia coli using ZYP5052 autoinduction media supplemented with 500 μM delta aminole...				US Patent US10988487 (2021) BindingDB Entry DOI: 10.7270/Q25T3PKG
					More data for this Ligand-Target Pair