Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Indoleamine 2,3-dioxygenase 1' and Ligand = 'BDBM50442986'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Indoleamine 2,3-dioxygenase 1 (Homo sapiens (Human))	BDBM50442986 (CHEMBL3087014) Show SMILES Fc1ccc-2c(c1)C(=O)c1nc3ccc(Cn4cc(nn4)-c4ccccc4)cc3c(=O)n-21 Show InChI InChI=1S/C24H14FN5O2/c25-16-7-9-21-18(11-16)22(31)23-26-19-8-6-14(10-17(19)24(32)30(21)23)12-29-13-20(27-28-29)15-4-2-1-3-5-15/h1-11,13H,12H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	6.33E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Fudan University Curated by ChEMBL					Assay Description Uncompetitive inhibition of human recombinant IDO1 using L-tryptophan as substrate				J Med Chem 56: 8321-31 (2013) Article DOI: 10.1021/jm401195n BindingDB Entry DOI: 10.7270/Q2X34ZWS
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Homo sapiens (Human))	BDBM50442986 (CHEMBL3087014) Show SMILES Fc1ccc-2c(c1)C(=O)c1nc3ccc(Cn4cc(nn4)-c4ccccc4)cc3c(=O)n-21 Show InChI InChI=1S/C24H14FN5O2/c25-16-7-9-21-18(11-16)22(31)23-26-19-8-6-14(10-17(19)24(32)30(21)23)12-29-13-20(27-28-29)15-4-2-1-3-5-15/h1-11,13H,12H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	185	n/a	n/a	n/a	n/a	n/a	n/a
Fudan University Curated by ChEMBL					Assay Description Inhibition of human IDO1 expressed in HEK293 cells assessed as kynurenine release after 5 hrs by spectrophotometry				J Med Chem 56: 8321-31 (2013) Article DOI: 10.1021/jm401195n BindingDB Entry DOI: 10.7270/Q2X34ZWS
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Homo sapiens (Human))	BDBM50442986 (CHEMBL3087014) Show SMILES Fc1ccc-2c(c1)C(=O)c1nc3ccc(Cn4cc(nn4)-c4ccccc4)cc3c(=O)n-21 Show InChI InChI=1S/C24H14FN5O2/c25-16-7-9-21-18(11-16)22(31)23-26-19-8-6-14(10-17(19)24(32)30(21)23)12-29-13-20(27-28-29)15-4-2-1-3-5-15/h1-11,13H,12H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.91E+4	n/a	n/a	n/a	n/a	n/a	n/a
Fudan University Curated by ChEMBL					Assay Description Uncompetitive inhibition of human recombinant IDO1 using L-tryptophan as substrate				J Med Chem 56: 8321-31 (2013) Article DOI: 10.1021/jm401195n BindingDB Entry DOI: 10.7270/Q2X34ZWS
					More data for this Ligand-Target Pair