Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Indoleamine 2,3-dioxygenase 1' and Ligand = 'BDBM50509627'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Indoleamine 2,3-dioxygenase 1 (Homo sapiens (Human))	BDBM50509627 (CHEMBL4475499) Show SMILES NS(=O)(=O)CC(=O)NCCSc1nonc1\C(Nc1cccc(c1)C(F)F)=N\O Show InChI InChI=1S/C14H16F2N6O5S2/c15-12(16)8-2-1-3-9(6-8)19-13(20-24)11-14(22-27-21-11)28-5-4-18-10(23)7-29(17,25)26/h1-3,6,12,24H,4-5,7H2,(H,18,23)(H,19,20)(H2,17,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Phenex Pharmaceuticals AG Curated by ChEMBL					Assay Description Inhibition of IDO1 in interferon-gamma-induced human SKOV3 cells assessed as N-formylkynurenine formation using L-tryptophan as substrate measured af...				ACS Med Chem Lett 11: 179-187 (2020) Article DOI: 10.1021/acsmedchemlett.9b00572 BindingDB Entry DOI: 10.7270/Q2GX4FWT
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Homo sapiens (Human))	BDBM50509627 (CHEMBL4475499) Show SMILES NS(=O)(=O)CC(=O)NCCSc1nonc1\C(Nc1cccc(c1)C(F)F)=N\O Show InChI InChI=1S/C14H16F2N6O5S2/c15-12(16)8-2-1-3-9(6-8)19-13(20-24)11-14(22-27-21-11)28-5-4-18-10(23)7-29(17,25)26/h1-3,6,12,24H,4-5,7H2,(H,18,23)(H,19,20)(H2,17,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Phenex Pharmaceuticals AG Curated by ChEMBL					Assay Description Inhibition of human N-terminal GST-tagged IDO1 expressed in Escherichia coli Rosetta(DE3) pLysS using L-tryptophan as substrate measured after 1 hr b...				ACS Med Chem Lett 11: 179-187 (2020) Article DOI: 10.1021/acsmedchemlett.9b00572 BindingDB Entry DOI: 10.7270/Q2GX4FWT
					More data for this Ligand-Target Pair