Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Induced myeloid leukemia cell differentiation protein Mcl-1' and Ligand = 'BDBM231591'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Induced myeloid leukemia cell differentiation protein Mcl-1 (Homo sapiens (Human))	BDBM231591 (US9345700, 26) Show SMILES O=C(Nc1cccnc1)c1cc(nc2ccc(cc12)-c1ccc2[nH]cnc2c1)-c1ccco1 Show InChI InChI=1S/C26H17N5O2/c32-26(30-18-3-1-9-27-14-18)20-13-24(25-4-2-10-33-25)31-21-7-5-16(11-19(20)21)17-6-8-22-23(12-17)29-15-28-22/h1-15H,(H,28,29)(H,30,32)	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Eutropics Pharmaceuticals, Inc. US Patent					Assay Description A streptavidin-coated plate (Thermo Scientific, NUNC #436014) was washed three times with 300 μL of PBS-0.05% Tween solution. A biotinylated twent...				US Patent US9345700 (2016) BindingDB Entry DOI: 10.7270/Q2J38RD4
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