Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Induced myeloid leukemia cell differentiation protein Mcl-1' and Ligand = 'BDBM231604'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Induced myeloid leukemia cell differentiation protein Mcl-1 (Homo sapiens (Human))	BDBM231604 (US9345700, 39) Show SMILES CN1CCN(CC1)C(=O)c1cc(nc2ccc(cc12)-c1ccc2scnc2c1)-c1ccco1 Show InChI InChI=1S/C26H22N4O2S/c1-29-8-10-30(11-9-29)26(31)20-15-22(24-3-2-12-32-24)28-21-6-4-17(13-19(20)21)18-5-7-25-23(14-18)27-16-33-25/h2-7,12-16H,8-11H2,1H3	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Eutropics Pharmaceuticals, Inc. US Patent					Assay Description A streptavidin-coated plate (Thermo Scientific, NUNC #436014) was washed three times with 300 μL of PBS-0.05% Tween solution. A biotinylated twent...				US Patent US9345700 (2016) BindingDB Entry DOI: 10.7270/Q2J38RD4
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