Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Induced myeloid leukemia cell differentiation protein Mcl-1 (Homo sapiens (Human)) | BDBM50339778![]() (CHEMBL1689140 | N-{7-[4-(4'-Chloro-biphenyl-2-ylme...) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Walter and Eliza Hall Institute of Medical Research Curated by ChEMBL | Assay Description Displacement of wild type mBimBH3 from Mcl-1 by solution competition assay | J Med Chem 54: 1914-26 (2011) Article DOI: 10.1021/jm101596e BindingDB Entry DOI: 10.7270/Q27P8ZP8 | |||||||||||
More data for this Ligand-Target Pair |