Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Inhibitor of nuclear factor kappa-B kinase subunit alpha' and Ligand = 'BDBM50130236'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Inhibitor of nuclear factor kappa-B kinase subunit alpha (Homo sapiens (Human))	BDBM50130236 (CHEMBL78885 | N-(6-Chloro-9H-beta-carbolin-8-yl)-4...) Show SMILES COc1ccc(cc1)C(=O)Nc1cc(Cl)cc2c3cc[nH]cc3nc12 Show InChI InChI=1S/C19H14ClN3O2/c1-25-13-4-2-11(3-5-13)19(24)23-16-9-12(20)8-15-14-6-7-21-10-17(14)22-18(15)16/h2-10,21H,1H3,(H,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibitory activity against IkappaB kinase(IKK) isolated from HeLa cells activated with recombinant MEEK1 in an ELISA phosphorylaton assay.				Bioorg Med Chem Lett 13: 2419-22 (2003) BindingDB Entry DOI: 10.7270/Q2PK0FJ7
					More data for this Ligand-Target Pair