Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Inosine-5'-monophosphate dehydrogenase' and Ligand = 'BDBM50535239'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Inosine-5'-monophosphate dehydrogenase (Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22...)	BDBM50535239 (CHEMBL4588651) Show SMILES OC(=O)c1cc(-c2cc(Br)ccc2F)c2c(n[nH]c2n1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C19H10BrClFN3O2/c20-10-3-6-14(22)12(7-10)13-8-15(19(26)27)23-18-16(13)17(24-25-18)9-1-4-11(21)5-2-9/h1-8H,(H,26,27)(H,23,24,25)	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
France; Universit£ Paris Diderot Curated by ChEMBL					Assay Description Inhibition of Pseudomonas aeruginosa IMPDH using IMP as substrate in the presence of NAD+ incubated for 70 secs				Eur J Med Chem 167: 124-132 (2019) Article DOI: 10.1016/j.ejmech.2019.01.064 BindingDB Entry DOI: 10.7270/Q2XK8K1C
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