Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Inosine-5'-monophosphate dehydrogenase 2' and Ligand = 'BDBM50456092'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Inosine-5'-monophosphate dehydrogenase 2 (Homo sapiens (Human))	BDBM50456092 (CHEMBL4218122) Show SMILES C[C@H](Oc1cccc(Cl)c1Cl)C(=O)Nc1ccc2oc(nc2c1)-c1ccc(cc1)-c1n[nH]c(=O)o1 |r| Show InChI InChI=1S/C24H16Cl2N4O5/c1-12(33-19-4-2-3-16(25)20(19)26)21(31)27-15-9-10-18-17(11-15)28-22(34-18)13-5-7-14(8-6-13)23-29-30-24(32)35-23/h2-12H,1H3,(H,27,31)(H,30,32)/t12-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Allergy and Infectious Diseases Curated by ChEMBL					Assay Description Inhibition of human IMPDH2 using IMP as substrate by spectrophotometric method				J Med Chem 61: 4739-4756 (2018) Article DOI: 10.1021/acs.jmedchem.7b01839 BindingDB Entry DOI: 10.7270/Q29889M0
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