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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Insulin-like growth factor 1 receptor' and Ligand = 'BDBM107007'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Insulin-like growth factor 1 receptor


(Homo sapiens (Human))
BDBM107007
PNG
(US8592579, 134)
Show SMILES C[C@]1(CCCN1c1nc(Nc2cc([nH]n2)C2CC2)c2cccn2n1)C(=O)Nc1cc(n[nH]1)C1CC1 |r|
Show InChI InChI=1S/C24H28N10O/c1-24(22(35)26-20-13-17(29-31-20)15-7-8-15)9-3-10-33(24)23-27-21(18-4-2-11-34(18)32-23)25-19-12-16(28-30-19)14-5-6-14/h2,4,11-15H,3,5-10H2,1H3,(H2,26,29,31,35)(H2,25,27,28,30,32)/t24-/m0/s1
PDB
MMDB

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Similars

US Patent
n/an/a 34n/an/an/an/a7.4n/a



Bristol-Myers Squibb Company

US Patent


Assay Description
Kinase assay using IGF1-receptor.


US Patent US8592579 (2013)


BindingDB Entry DOI: 10.7270/Q2SQ8Z12
More data for this
Ligand-Target Pair