Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Insulin-like growth factor 1 receptor (Homo sapiens (Human)) | BDBM50340520 (5,5-dimethyl-1-(quinolin-4-ylmethyl)-3-(4-(trifluo...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 460 | n/a | n/a | n/a | n/a | n/a | n/a |
Sanofi-aventis Curated by ChEMBL | Assay Description Inhibition of IGF-induced autophosphosphorylation of GST-tagged human IGF1R expressed in SF21 cells by time resolved-fluorescent assay | Bioorg Med Chem Lett 21: 2224-8 (2011) Article DOI: 10.1016/j.bmcl.2011.03.003 BindingDB Entry DOI: 10.7270/Q2CC11PK | |||||||||||
More data for this Ligand-Target Pair |