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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Insulin-like growth factor 1 receptor' and Ligand = 'BDBM50349720'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Insulin-like growth factor 1 receptor


(Homo sapiens (Human))
BDBM50349720
PNG
(CHEMBL1809063)
Show SMILES COc1cc(ccc1Nc1ncc(Cl)c(n1)-c1cnc2ccccn12)N1CCN(CC(=O)N(C)C)CC1
Show InChI InChI=1S/C26H29ClN8O2/c1-32(2)24(36)17-33-10-12-34(13-11-33)18-7-8-20(22(14-18)37-3)30-26-29-15-19(27)25(31-26)21-16-28-23-6-4-5-9-35(21)23/h4-9,14-16H,10-13,17H2,1-3H3,(H,29,30,31)
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Article
PubMed
n/an/a 12n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Inhibition of auto-phosphorylation of IGFR1


Bioorg Med Chem Lett 21: 4702-4 (2011)


Article DOI: 10.1016/j.bmcl.2011.06.090
BindingDB Entry DOI: 10.7270/Q2QZ2B9Q
More data for this
Ligand-Target Pair
Insulin-like growth factor 1 receptor


(Homo sapiens (Human))
BDBM50349720
PNG
(CHEMBL1809063)
Show SMILES COc1cc(ccc1Nc1ncc(Cl)c(n1)-c1cnc2ccccn12)N1CCN(CC(=O)N(C)C)CC1
Show InChI InChI=1S/C26H29ClN8O2/c1-32(2)24(36)17-33-10-12-34(13-11-33)18-7-8-20(22(14-18)37-3)30-26-29-15-19(27)25(31-26)21-16-28-23-6-4-5-9-35(21)23/h4-9,14-16H,10-13,17H2,1-3H3,(H,29,30,31)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 40n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Inhibition of auto-phosphorylation of IGFR1 by cell based assay


Bioorg Med Chem Lett 21: 4702-4 (2011)


Article DOI: 10.1016/j.bmcl.2011.06.090
BindingDB Entry DOI: 10.7270/Q2QZ2B9Q
More data for this
Ligand-Target Pair