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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Integrin alpha-5/beta-6' and Ligand = 'BDBM465227'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Integrin alpha-5/beta-6


(Homo sapiens (Human))		BDBM465227
PNG
(US10793564, Compound 16 | US11419869, Compound 16 ...)
Show SMILES COCCN(CCCCc1ccc2CCCNc2n1)CC[C@H](Nc1ncnc2cccnc12)C(O)=O
Show InChI InChI=1S/C26H35N7O3/c1-36-17-16-33(14-3-2-7-20-10-9-19-6-4-13-28-24(19)31-20)15-11-22(26(34)35)32-25-23-21(29-18-30-25)8-5-12-27-23/h5,8-10,12,18,22H,2-4,6-7,11,13-17H2,1H3,(H,28,31)(H,34,35)(H,29,30,32)/t22-/m0/s1
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US Patent
n/an/a<50n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25° C., overnight). The coating soluti...

US Patent US10793564 (2020)


BindingDB Entry DOI: 10.7270/Q2J969FH
More data for this
Ligand-Target Pair