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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Integrin alpha-5/beta-6' and Ligand = 'BDBM465229'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Integrin alpha-5/beta-6


(Homo sapiens (Human))		BDBM465229
PNG
(US10793564, Compound 18 | US11419869, Compound 18 ...)
Show SMILES COCCN(CCCCc1ccc2CCCNc2n1)CC[C@H](Nc1ncnc2cccc(F)c12)C(O)=O
Show InChI InChI=1S/C27H35FN6O3/c1-37-17-16-34(14-3-2-7-20-11-10-19-6-5-13-29-25(19)32-20)15-12-23(27(35)36)33-26-24-21(28)8-4-9-22(24)30-18-31-26/h4,8-11,18,23H,2-3,5-7,12-17H2,1H3,(H,29,32)(H,35,36)(H,30,31,33)/t23-/m0/s1
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US Patent
n/an/a<50n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25° C., overnight). The coating soluti...

US Patent US10793564 (2020)


BindingDB Entry DOI: 10.7270/Q2J969FH
More data for this
Ligand-Target Pair