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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Integrin alpha-5/beta-6' and Ligand = 'BDBM465234'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Integrin alpha-5/beta-6


(Homo sapiens (Human))		BDBM465234
PNG
(US10793564, Compound 23 | US11419869, Compound 23 ...)
Show SMILES COCCN(CCCCc1ccc2CCCNc2n1)CC[C@H](Nc1cc(ncn1)C(F)F)C(O)=O
Show InChI InChI=1S/C24H34F2N6O3/c1-35-14-13-32(11-3-2-6-18-8-7-17-5-4-10-27-23(17)30-18)12-9-19(24(33)34)31-21-15-20(22(25)26)28-16-29-21/h7-8,15-16,19,22H,2-6,9-14H2,1H3,(H,27,30)(H,33,34)(H,28,29,31)/t19-/m0/s1
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US Patent
n/an/a<50n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25° C., overnight). The coating soluti...

US Patent US10793564 (2020)


BindingDB Entry DOI: 10.7270/Q2J969FH
More data for this
Ligand-Target Pair