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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Integrin alpha-5/beta-6' and Ligand = 'BDBM465259'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Integrin alpha-5/beta-6


(Homo sapiens (Human))		BDBM465259
PNG
(US10793564, Compound 48 | US11419869, Compound 48 ...)
Show SMILES OC(=O)[C@H](CCN(CCCCc1ccc2CCCNc2n1)CCOc1ccccn1)Nc1ncnc2c(Cl)cccc12
Show InChI InChI=1S/C31H36ClN7O3/c32-25-10-5-9-24-28(25)35-21-36-30(24)38-26(31(40)41)14-18-39(19-20-42-27-11-1-3-15-33-27)17-4-2-8-23-13-12-22-7-6-16-34-29(22)37-23/h1,3,5,9-13,15,21,26H,2,4,6-8,14,16-20H2,(H,34,37)(H,40,41)(H,35,36,38)/t26-/m0/s1
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US Patent
n/an/a<50n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25° C., overnight). The coating soluti...

US Patent US10793564 (2020)


BindingDB Entry DOI: 10.7270/Q2J969FH
More data for this
Ligand-Target Pair