Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Integrin alpha-L' and Ligand = 'BDBM50107178'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Integrin alpha-L (Homo sapiens (Human))	BDBM50107178 (5-[3-(4-Acetyl-piperazin-1-yl)-3-oxo-propenyl]-2-(...) Show SMILES CN(C)S(=O)(=O)c1cc(\C=C\C(=O)N2CCN(CC2)C(C)=O)ccc1Sc1cccc(Cl)c1Cl Show InChI InChI=1S/C23H25Cl2N3O4S2/c1-16(29)27-11-13-28(14-12-27)22(30)10-8-17-7-9-19(21(15-17)34(31,32)26(2)3)33-20-6-4-5-18(24)23(20)25/h4-10,15H,11-14H2,1-3H3/b10-8+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	3.75E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of intercellular adhesion molecule-1 (ICAM-1) binding to recombinant LFA-1, range(3700-3800)				J Med Chem 44: 4393-403 (2001) BindingDB Entry DOI: 10.7270/Q2WW7GZN
					More data for this Ligand-Target Pair