Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Integrin alpha-V/beta-3' and Ligand = 'BDBM50072510'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50072510 (CHEMBL419013 | {(S)-4-Methyl-7-[methyl-(7H-purin-8...) Show SMILES CN(Cc1nc2ncncc2[nH]1)C(=O)c1ccc2N[C@@H](CC(O)=O)C(=O)N(C)Cc2c1 Show InChI InChI=1S/C20H21N7O4/c1-26-8-12-5-11(3-4-13(12)23-14(20(26)31)6-17(28)29)19(30)27(2)9-16-24-15-7-21-10-22-18(15)25-16/h3-5,7,10,14,23H,6,8-9H2,1-2H3,(H,28,29)(H,21,22,24,25)/t14-/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	23	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Antagonistic activity for human vitronectin receptor (alphaV-beta3) from platelets				Bioorg Med Chem Lett 8: 3171-6 (1999) BindingDB Entry DOI: 10.7270/Q2B85994
					More data for this Ligand-Target Pair