Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Integrin alpha-V/beta-3' and Ligand = 'BDBM50083773'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50083773 (2-(Biphenyl-4-sulfonylamino)-3-({5-[4-(pyridin-2-y...) Show SMILES CN([C@@H](CNC(=O)C1=NOC(CCCCNc2ccccn2)C1)C(O)=O)S(=O)(=O)c1ccc(cc1)-c1ccccc1 |t:7| Show InChI InChI=1S/C29H33N5O6S/c1-34(41(38,39)24-15-13-22(14-16-24)21-9-3-2-4-10-21)26(29(36)37)20-32-28(35)25-19-23(40-33-25)11-5-7-17-30-27-12-6-8-18-31-27/h2-4,6,8-10,12-16,18,23,26H,5,7,11,17,19-20H2,1H3,(H,30,31)(H,32,35)(H,36,37)/t23?,26-/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Inhibition of vitronectin receptor (alpha V beta 3), expressed on human 293 cells, binding to immobilized fibrinogen				J Med Chem 43: 27-40 (2000) BindingDB Entry DOI: 10.7270/Q2571B77
					More data for this Ligand-Target Pair