Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Integrin alpha-V/beta-3' and Ligand = 'BDBM50083778'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50083778 (2-(Biphenyl-4-sulfonylamino)-3-({5-[4-(1H-imidazol...) Show SMILES OC(=O)[C@H](CNC(=O)C1=NOC(CCCCNc2ncc[nH]2)C1)NS(=O)(=O)c1ccc(cc1)-c1ccccc1 |t:8| Show InChI InChI=1S/C26H30N6O6S/c33-24(22-16-20(38-31-22)8-4-5-13-27-26-28-14-15-29-26)30-17-23(25(34)35)32-39(36,37)21-11-9-19(10-12-21)18-6-2-1-3-7-18/h1-3,6-7,9-12,14-15,20,23,32H,4-5,8,13,16-17H2,(H,30,33)(H,34,35)(H2,27,28,29)/t20?,23-/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Inhibition of vitronectin receptor (alpha V beta 3), expressed on human 293 cells, binding to immobilized fibrinogen				J Med Chem 43: 27-40 (2000) BindingDB Entry DOI: 10.7270/Q2571B77
					More data for this Ligand-Target Pair