Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Integrin alpha-V/beta-3' and Ligand = 'BDBM50083791'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50083791 (3-({5-[3-(6-Amino-pyridin-2-yl)-propyl]-4,5-dihydr...) Show SMILES Cc1cc(C)c(c(C)c1)S(=O)(=O)N[C@@H](CNC(=O)C1=NOC(CCCc2cccc(N)n2)C1)C(O)=O |t:19| Show InChI InChI=1S/C24H31N5O6S/c1-14-10-15(2)22(16(3)11-14)36(33,34)29-20(24(31)32)13-26-23(30)19-12-18(35-28-19)8-4-6-17-7-5-9-21(25)27-17/h5,7,9-11,18,20,29H,4,6,8,12-13H2,1-3H3,(H2,25,27)(H,26,30)(H,31,32)/t18?,20-/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Inhibition of vitronectin receptor (alpha V beta 3), expressed on human 293 cells, binding to immobilized fibrinogen				J Med Chem 43: 27-40 (2000) BindingDB Entry DOI: 10.7270/Q2571B77
					More data for this Ligand-Target Pair