Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Integrin alpha-V/beta-3 (Homo sapiens (Human)) | BDBM50195100![]() ((Z)-N-(2,6-dimethoxypyrimidin-4-yl)-4-((1-(4-iodop...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 5.35E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Medical Sciences and Peking Union Medical College Curated by ChEMBL | Assay Description Inhibition of integrin alphavbeta3 mediated cell adhesion of human M21 cells to vitronectiin | Bioorg Med Chem Lett 16: 5878-82 (2006) Article DOI: 10.1016/j.bmcl.2006.08.061 BindingDB Entry DOI: 10.7270/Q2W66N0W | |||||||||||
More data for this Ligand-Target Pair |