Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Integrin alpha-V/beta-3' and Ligand = 'BDBM50327747'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50327747 ((R)-3-{2-[4-(2-Guanidinoethyl)[1,2,3]triazol-1-yl]...) Show SMILES [#7]\[#6](-[#7])=[#7]\[#6]-[#6]-c1cn(-[#6]-[#6](=O)-[#7]-[#6@H](-[#6](-[#8])=O)-c2ccccc2)nn1 |r| Show InChI InChI=1S/C15H19N7O3/c16-15(17)18-7-6-11-8-22(21-20-11)9-12(23)19-13(14(24)25)10-4-2-1-3-5-10/h1-5,8,13H,6-7,9H2,(H,19,23)(H,24,25)(H4,16,17,18)/t13-/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Florence Curated by ChEMBL					Assay Description Displacement of [125I]echistatin from human integrin alphaVbeta3				J Med Chem 53: 7119-28 (2010) Article DOI: 10.1021/jm100754z BindingDB Entry DOI: 10.7270/Q2R211NF
					More data for this Ligand-Target Pair