BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Integrin alpha-V/beta-6' and Ligand = 'BDBM50519159'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Integrin alpha-V/beta-6


(Homo sapiens (Human))		BDBM50519159
PNG
(CHEMBL4589933)
Show SMILES C[N+]1(C[C@@H](CC([O-])=O)c2cccc(O[C@@H]3CCOC3)c2)CC[C@@H](CCc2ccc3CCCNc3n2)C1 |r|
Show InChI InChI=1S/C29H39N3O4/c1-32(14-11-21(18-32)7-9-25-10-8-22-5-3-13-30-29(22)31-25)19-24(17-28(33)34)23-4-2-6-26(16-23)36-27-12-15-35-20-27/h2,4,6,8,10,16,21,24,27H,3,5,7,9,11-15,17-20H2,1H3,(H-,30,31,33,34)/t21-,24-,27-,32?/m1/s1
PDB

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 13n/an/an/an/an/an/a



GlaxoSmithKline Medicines Research Centre

Curated by ChEMBL


Assay Description
Inhibition of integrin alphavbeta6 (unknown origin) expressed in human K562 cells assessed as reduction in cell adhesion to GST-LAP1 (242 to 252 amin...

J Med Chem 62: 7543-7556 (2019)


Article DOI: 10.1021/acs.jmedchem.9b00819
BindingDB Entry DOI: 10.7270/Q2S75KQH
More data for this
Ligand-Target Pair