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Found 1 hit Enz. Inhib. hit(s) with Target = 'Interleukin-1 receptor antagonist protein' and Ligand = 'BDBM50519949'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Interleukin-1 receptor antagonist protein


(Mus musculus)		BDBM50519949
PNG
(CHEMBL4458647)
Show SMILES OC(=O)c1ccc(Cl)c(c1)S(=O)(=O)Nc1cc(ccc1N1CCCCC1)C(F)(F)F
Show InChI InChI=1S/C19H18ClF3N2O4S/c20-14-6-4-12(18(26)27)10-17(14)30(28,29)24-15-11-13(19(21,22)23)5-7-16(15)25-8-2-1-3-9-25/h4-7,10-11,24H,1-3,8-9H2,(H,26,27)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>2.00E+5n/an/an/an/an/an/a



Kansas University Specialized Chemistry Center

Curated by ChEMBL


Assay Description
Inhibition of recombinant mouse C-terminal His6-tagged IRAP expressed in baculovirus infected BTA-TN-5B1-4 insect cells using L-AMC as substrate meas...

J Med Chem 63: 103-121 (2020)


Article DOI: 10.1021/acs.jmedchem.9b00293
BindingDB Entry DOI: 10.7270/Q2DN48D3
More data for this
Ligand-Target Pair