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Found 1 hit Enz. Inhib. hit(s) with Target = 'Interleukin-1 receptor antagonist protein' and Ligand = 'BDBM50519956'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Interleukin-1 receptor antagonist protein


(Mus musculus)		BDBM50519956
PNG
(CHEMBL4558482)
Show SMILES COc1ccc(cc1S(=O)(=O)Nc1ccccc1N1CCCCC1)C(O)=O
Show InChI InChI=1S/C19H22N2O5S/c1-26-17-10-9-14(19(22)23)13-18(17)27(24,25)20-15-7-3-4-8-16(15)21-11-5-2-6-12-21/h3-4,7-10,13,20H,2,5-6,11-12H2,1H3,(H,22,23)
UniProtKB/SwissProt

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a>2.00E+5n/an/an/an/an/an/a



Kansas University Specialized Chemistry Center

Curated by ChEMBL


Assay Description
Inhibition of recombinant mouse C-terminal His6-tagged IRAP expressed in baculovirus infected BTA-TN-5B1-4 insect cells using L-AMC as substrate meas...

J Med Chem 63: 103-121 (2020)


Article DOI: 10.1021/acs.jmedchem.9b00293
BindingDB Entry DOI: 10.7270/Q2DN48D3
More data for this
Ligand-Target Pair