BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Interleukin-15' and Ligand = 'BDBM50571049'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Interleukin-15


(Mus musculus)
BDBM50571049
PNG
(CHEMBL4868024)
Show SMILES CCOC(CCn1c(Cc2nn(C)c(=O)c3ccccc23)nnc1SCCCCCCCC(=O)Nc1ccc(Cl)cc1Cl)OCC
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.21E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of IL-15 in mouse 32Dbeta cells assessed as decrease in cell growth in presence of RLI incubated for 30 mins followed by RLI addition and ...


Citation and Details

Article DOI: 10.1016/j.bmc.2021.116161
BindingDB Entry DOI: 10.7270/Q2FF3X47
More data for this
Ligand-Target Pair
Interleukin-15


(Mus musculus)
BDBM50571049
PNG
(CHEMBL4868024)
Show SMILES CCOC(CCn1c(Cc2nn(C)c(=O)c3ccccc23)nnc1SCCCCCCCC(=O)Nc1ccc(Cl)cc1Cl)OCC
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.64E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of IL-15 in mouse 32Dbeta cells assessed as decrease in cell growth in presence of IL2 incubated for 30 mins followed by IL2 addition and ...


Citation and Details

Article DOI: 10.1016/j.bmc.2021.116161
BindingDB Entry DOI: 10.7270/Q2FF3X47
More data for this
Ligand-Target Pair
Interleukin-15


(Homo sapiens)
BDBM50571049
PNG
(CHEMBL4868024)
Show SMILES CCOC(CCn1c(Cc2nn(C)c(=O)c3ccccc23)nnc1SCCCCCCCC(=O)Nc1ccc(Cl)cc1Cl)OCC
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 3.00E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of IL-15-induced STAT3 phosphorylation in human NK92 cells incubated for 30 mins followed by IL-15 stimulation and measured after 1 hr by ...


Citation and Details

Article DOI: 10.1016/j.bmc.2021.116161
BindingDB Entry DOI: 10.7270/Q2FF3X47
More data for this
Ligand-Target Pair