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Found 3 hits Enz. Inhib. hit(s) with Target = 'Interleukin-15' and Ligand = 'BDBM50571056'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Interleukin-15


(Mus musculus)
BDBM50571056
PNG
(CHEMBL4863838)
Show SMILES [#6]-n1c(-[#6]-c2nn(-[#6]-[#6]-[#6]-[#8][Si;v4]([#6])([#6])C([#6])([#6])[#6])c(=O)c3ccccc23)nnc1-[#16]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6](=O)-[#7]-c1ccc(Cl)cc1Cl
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>3.00E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of IL-15 in mouse 32Dbeta cells assessed as decrease in cell growth in presence of RLI incubated for 30 mins followed by RLI addition and ...


Citation and Details

Article DOI: 10.1016/j.bmc.2021.116161
BindingDB Entry DOI: 10.7270/Q2FF3X47
More data for this
Ligand-Target Pair
Interleukin-15


(Homo sapiens)
BDBM50571056
PNG
(CHEMBL4863838)
Show SMILES [#6]-n1c(-[#6]-c2nn(-[#6]-[#6]-[#6]-[#8][Si;v4]([#6])([#6])C([#6])([#6])[#6])c(=O)c3ccccc23)nnc1-[#16]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6](=O)-[#7]-c1ccc(Cl)cc1Cl
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>3.00E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of IL-15-induced STAT3 phosphorylation in human NK92 cells incubated for 30 mins followed by IL-15 stimulation and measured after 1 hr by ...


Citation and Details

Article DOI: 10.1016/j.bmc.2021.116161
BindingDB Entry DOI: 10.7270/Q2FF3X47
More data for this
Ligand-Target Pair
Interleukin-15


(Mus musculus)
BDBM50571056
PNG
(CHEMBL4863838)
Show SMILES [#6]-n1c(-[#6]-c2nn(-[#6]-[#6]-[#6]-[#8][Si;v4]([#6])([#6])C([#6])([#6])[#6])c(=O)c3ccccc23)nnc1-[#16]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6](=O)-[#7]-c1ccc(Cl)cc1Cl
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>3.00E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of IL-15 in mouse 32Dbeta cells assessed as decrease in cell growth in presence of IL2 incubated for 30 mins followed by IL2 addition and ...


Citation and Details

Article DOI: 10.1016/j.bmc.2021.116161
BindingDB Entry DOI: 10.7270/Q2FF3X47
More data for this
Ligand-Target Pair