Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Interleukin-2' and Ligand = 'BDBM387294'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Interleukin-2 (Homo sapiens (Human))	BDBM387294 (US10292981, Example 78) Show SMILES Cc1ccc(cc1-c1cnc(NC(=O)c2ccccc2Cl)cn1)C1=NOC(C)(C)C1=O |t:26| Show InChI InChI=1S/C23H19ClN4O3/c1-13-8-9-14(20-21(29)23(2,3)31-28-20)10-16(13)18-11-26-19(12-25-18)27-22(30)15-6-4-5-7-17(15)24/h4-12H,1-3H3,(H,26,27,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	171	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of PHA-stimulated IL2 secretion in human Jurkat T cells preincubated for 10 mins followed by PHA addition and measured after 20 to 24 hrs ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01403 BindingDB Entry DOI: 10.7270/Q2C82F4Q
					More data for this Ligand-Target Pair
Interleukin-2 (Homo sapiens (Human))	BDBM387294 (US10292981, Example 78) Show SMILES Cc1ccc(cc1-c1cnc(NC(=O)c2ccccc2Cl)cn1)C1=NOC(C)(C)C1=O |t:26| Show InChI InChI=1S/C23H19ClN4O3/c1-13-8-9-14(20-21(29)23(2,3)31-28-20)10-16(13)18-11-26-19(12-25-18)27-22(30)15-6-4-5-7-17(15)24/h4-12H,1-3H3,(H,26,27,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description Jurkat T cells were seeded at a density of 0.5 to 1 million cells per well in RPMI medium. Test compounds from this invention were added to the cells...				Bioorg Med Chem Lett 18: 1958-62 (2008) BindingDB Entry DOI: 10.7270/Q2D50Q8B
					More data for this Ligand-Target Pair