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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Interleukin-2' and Ligand = 'BDBM50587596'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Interleukin-2


(Homo sapiens (Human))
BDBM50587596
PNG
(CHEMBL5086824 | US11661419, Example 36 | US2023028...)
Show SMILES [H][C@@]12C[C@]1(C)Cc1[nH]nc(c1C2)-c1nc2cc(N(C)C(=O)CN3CCOCC3=O)c(C)cc2[nH]1 |r|
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 96n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of IL-2 in CD3/CD28 activated human CD4+ve Th cells preincubated for 15 mins followed by addition of immuno-cult and measured after 24 hrs...


Citation and Details

Article DOI: 10.1021/acsmedchemlett.1c00619
BindingDB Entry DOI: 10.7270/Q2736VT6
More data for this
Ligand-Target Pair