Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Interleukin-2 receptor subunit alpha (Homo sapiens (Human)) | BDBM50147974 ((S)-2-[2-((R)-1-Carbamimidoyl-piperidin-3-yl)-acet...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents | n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Assay Description Antagonist activity at adrenergic Alpha-1D receptor in rat aorta | Citation and Details | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Interleukin-2 receptor subunit alpha (Mus musculus) | BDBM50147974 ((S)-2-[2-((R)-1-Carbamimidoyl-piperidin-3-yl)-acet...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents | Article PubMed | n/a | n/a | 6.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sunesis Pharmaceuticals Inc. Curated by ChEMBL | Assay Description Inhibition of mouse Interleukin-2 receptor alpha | J Med Chem 47: 3111-30 (2004) Article DOI: 10.1021/jm049967u BindingDB Entry DOI: 10.7270/Q2TQ6280 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Interleukin-2 receptor subunit alpha (Homo sapiens (Human)) | BDBM50147974 ((S)-2-[2-((R)-1-Carbamimidoyl-piperidin-3-yl)-acet...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents | Article | n/a | n/a | 6.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Competitive inhibition of IL2 receptor alpha (unknown origin) | Citation and Details Article DOI: 10.1007/s00044-013-0564-x BindingDB Entry DOI: 10.7270/Q20V8GP1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Interleukin-2 receptor subunit alpha (Mus musculus) | BDBM50147974 ((S)-2-[2-((R)-1-Carbamimidoyl-piperidin-3-yl)-acet...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents | Article PubMed | n/a | n/a | n/a | n/a | 1.00E+5 | n/a | n/a | n/a | n/a |
Sunesis Pharmaceuticals Inc. Curated by ChEMBL | Assay Description Effective concentration required against phosphorylation of Mammary gland factor/STAT5 | J Med Chem 47: 3111-30 (2004) Article DOI: 10.1021/jm049967u BindingDB Entry DOI: 10.7270/Q2TQ6280 | |||||||||||
More data for this Ligand-Target Pair |